Neurological Glossary

Neurological terms are often complicated and difficult to understand. The following glossary defines a variety of terms to help you understand neurological terminology:

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Echocardiogram

An ultrasound examination of the heart

    Echolalia

    The echoing or repetition of verbal utterances made by another person

      Echopraxia

      Imitative repetition of the movements

        Edinger-Westphal nucleus

        Accessory nucleus of each oculomotor nerve that supplies preganglionic parasympathetic fibers for pupillary constriction and lens accommodation; located in the midline between the extraocular oculomotor nerve nuclei

          Efferent

          Motor pathway proceeding from the CNS toward the peripheral end organs

            Eidetic memory (photographic memory)

            Ability to vividly recall visual images

              Electroencephalogram (EEG)

              Test that measures and records the electrical activity of the brain by using sensors (electrodes) attached to the head.

                Electronic aids

                Assistive devices

                  Eloquent cortex

                  Regions of the cerebral cortex responsible for motor

                    Embolism

                    The blockage of a blood vessel by an embolus'something previously circulating in the blood (such as a blood clot

                      Emotional liability

                      A state of emotional disinhibition

                        Encephalitis

                        Inflammation of the brain

                          Encephalocele

                          Failure of bone fusion in the posterior midline of the skull resulting in a bony cleft through which meninges and/or brain parenchyma protrude

                            Encephalomalacia

                            Focal softening of the brain in areas of tissue death following cerebral infarction

                              Encephalopathy

                              Meaning

                                Endomysium

                                Innermost layer of connective tissue that forms an interstitial layer around each individual muscle fibre

                                  Endoneurium (epilemma)

                                  Innermost layer of connective tissue of a peripheral nerve that forms an interstitial layer around each individual axon / Schwann cell unit

                                    Enophthalmos

                                    Recession of the eyeball within the orbit

                                      Eosinophilic neuronal necrosis

                                      Neuronal response to ischemia and hypoxia characterized by brightly eosinophilic (red) cytoplasm and nuclear shrinkage

                                        Ependyma

                                        Epithelial lining of the ventricles of the brain and the canal of the spinal cord

                                          Ependymal cells

                                          Type of glia consisting of cuboidal cells lining the adult ventricles and spinal canal

                                            Ependymal true rosette

                                            Halo of cells surrounding an empty lumen; fairly specific for

                                              Ependymoma

                                              WHO grade II primary CNS tumour of children (involving the 4th ventricle) and young adults (involving the spinal cord); characterized histologically by perivascular pseudorosettes

                                                Ephaptic

                                                Electrical conduction of a nerve impulse across a non-synaptic contact site between nerves and without the mediation of a neurotransmitter

                                                  Epilepsy

                                                  A neurological condition originating in the brain and involving abnormal electrical activity in the brain which causes seizures of varying degree

                                                    Epilepsy syndrome

                                                    Disorder defined by seizure type

                                                      Epineurium

                                                      Outermost layer of a peripheral nerve containing connective tissue and an anastomotic vascular network

                                                        Epiphyseal Plate

                                                        The layer of cartilage between the diaphysis and epiphysis

                                                          Epiphysis

                                                          A secondary centre of ossification

                                                            Epithalamus

                                                            Dorsal posterior subdivision of the diencephalon generally considered to include the habenula

                                                              Equinus

                                                              Abnormality of foot which prevents normal weight-bearing

                                                                Equilibrium Reaction

                                                                Balance reaction

                                                                  Esotropia

                                                                  An eye with strabismus that deviates inward

                                                                    Essential tremor

                                                                    Medium or high frequency (4-9 Hz) tremor that occurs with action or holding a sustained posture that typically affects the arms

                                                                      Eversion

                                                                      Turning the sole of the foot away from the median plane

                                                                        Evoked potentials

                                                                        Recordings of the nervous system's electrical response to the stimulation of specific sensory pathways

                                                                          Excessive daytime sleepiness (hypersomnolence)

                                                                          Subjective difficulty in staying awake and easily falling asleep when sedentary

                                                                            Executive functions

                                                                            Higher intellectual functions such as judgment

                                                                              Exotropia

                                                                              An eye with strabismus that deviates outward

                                                                                Expanded Disability Status Scale (EDSS)

                                                                                20-point scale

                                                                                  Extension

                                                                                  Straightening

                                                                                    Extensor plantar response

                                                                                    Extension of the great toe ('upgoing toe') with fanning of the other toes in response to application of a stimulus to the skin of the foot or leg; signifies a lesion of the corticospinal tract

                                                                                      Extensor posturing

                                                                                      Stereotyped posture occurring in coma in response to stimulation in which the arms and legs extend (hips and shoulders extend

                                                                                        Extensor response in the arm

                                                                                        Stereotyped posture occurring in coma in response to stimulation in which the upper extremity extends (shoulder extends

                                                                                          Extensor spasm

                                                                                          Manifestation of spasticity in which the legs involuntarily straighten into an extended position where they remain for several minutes

                                                                                            External

                                                                                            Outside

                                                                                              Extra-axial

                                                                                              Within the skull or vertebral column but outside of the brain or spinal cord

                                                                                                Extracranial-intracranial bypass

                                                                                                Surgery to restore blood flow to an area of brain tissue by re-routing a healthy artery in the scalp to the area of brain tissue affected by a blocked or narrowed artery

                                                                                                  Extrapyramidal

                                                                                                  Movement disorder not involving the corticospinal tracts; typically refers to basal ganglia or cerebellar disorders

                                                                                                    Extrasylvian

                                                                                                    Outside of the area surrounding the Sylvian fissure; often used synonymously with