Neurological Glossary

Neurological terms are often complicated and difficult to understand. The following glossary defines a variety of terms to help you understand neurological terminology:

Browse A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Abulia

Loss of will, impulse, and decision-making ability.

  • Ford
  • BMW
  • Fiat

Acalculia

Inability to do the most simple calculations.

    Acupuncture

    A traditional Chinese system of healing in which symptoms are relieved by having thin metal needles inserted into selected points beneath the skin. The needles may be stimulated either by rotation or by an electric current and are then removed. If in any doubt about your condition, you should consult your doctor.

      Acute stroke

      The critical stage of stroke, starting at the onset of symptoms and lasting until the patient's condition is stabilised and they enter recovery

        Action tremor

        Tremor that appears during movement of the affected body part

          Adaptations

          Modifications to the built environment designed to assist access, mobility and self reliance; such as ramps, rails, roll-in showers and stair lifts.

            ADL

            Activities of Daily Living. The routine tasks that we all have to perform to live independently, such as washing, dressing, using the toilet, bathing, walking and climbing stairs.

              Afferent

              Sensory pathway proceeding toward the CNS from the peripheral receptor organs

                AFO

                Ankle Foot Orthosis. A brace used to stretch the Achilles tendon. This is usually made of thin, light plastic material, which the orthosis is individually moulded and will require replacement as the child grows.

                  Agnosia

                  Inability to recognise objects or sounds due to lack of perceptive capacity, although general intelligence is normal.

                  • Auditory agnosia, where the person's hearing is normal but he is unable to understand what words mean.
                  • Finger agnosia (sometimes used as a test for cerebral palsy), where a person is unable to identify individual fingers when, for example, they are touched by another person
                  • Tactile agnosia, where a person is unable to identify familiar objects by touch alone although he is aware that he is touching something.
                  • Visual agnosia, where a person is able to see but unable to express ideas in words.

                  Aphasia

                  A specific defect to brain function which leads to:

                  • Expressive aphasia, when a person is unable to express ideas in words.
                  • Receptive aphasia, when a person is unable to understand spoken language.

                  Agraphia

                  Inability to express thoughts in writing or by drawing.

                    Akinesia

                    Paucity of movement

                      Akinetic mutism

                      Disorder of consciousness characterized by periods of sleep and periods of wakefulness during which the patient lies with eyes open but is unresponsive, mute, and immobile; often due to frontal lobe damage.

                        Alexia

                        Inability to read, usually due to a lesion of dominant occipitotemporal cortex

                          Alien hand syndrome

                          Syndrome characterized by the involuntary movement of a single upper limb in conjunction with the experience of estrangement from or personification of the movements of the limb; often seen in corticobasal degeneration

                            Allodynia

                            Condition in which an ordinarily painless stimulus is experienced as being painful

                              Alpha motor neurons

                              Large motor neurons that innervate extrafusal skeletal muscle fibers

                                Alexia

                                Inability to read.

                                  Alignment

                                  Straight position.

                                    Alzheimer's disease

                                    Most common cause of dementia in older adults; a neurodegenerative disease characterized by the gradual loss of cognitive ability in association with the neuropathological findings of abnormal protein aggregates (neuritic plaques and neurofibrillary tangles) and neuron loss in the cerebral cortex

                                      Amaurosis Fugax

                                      A temporary loss of vision in one eye due to a blood clot blocking the flow of blood to the eye. There is complete recovery within 24 hours.

                                        Amblyopia

                                        Developmental abnormality in which a child fails to develop sharp visual acuity

                                          Ambulatory

                                          Able to walk.

                                            Amnesia

                                            Loss of memory.

                                              Amyotrophic lateral sclerosis

                                              (Lou Gehrig's disease) inexorably progressive and fatal disease of unknown cause characterized by slowly progressive degeneration of upper and lower motor neurons

                                                Analgesia

                                                Loss of pain sensation

                                                  Anencephaly (aprosencephaly)

                                                  CNS malformation involving failure of closure of the cephalic end of the neural tube

                                                    Aneurysm (brain aneurysm

                                                    cerebral aneurysm)

                                                      Anomia

                                                      Inability to name objects or to recognize written or spoken names of objects

                                                        Anosmia

                                                        Loss of sense

                                                          Anoxia

                                                          Lack of oxygen to the brain or other vital organs

                                                            Anterior cerebral artery

                                                            A branch of the internal carotid artery; supplies blood to the medial aspect of the cerebral cortex (leg area predominant)

                                                              Anterior commissure

                                                              One of the three major groups of commissural fibers that courses through the basal ganglia and cross the midline in the anterior forebrain to interconnect the olfactory bulbs

                                                                Anterior communicating artery

                                                                Branch of the internal carotid artery that joins together the paired anterior cerebral arteries

                                                                  Anterior cord syndrome

                                                                  Spinal cord injury syndrome associated with damage to the anterior 2/3 of the spinal cord

                                                                    Anterior cranial fossa

                                                                    Portion of the internal base of the skull housing the frontal lobes

                                                                      Anterior horn (ventral horn)

                                                                      Gray matter in the front of the spinal cord that contains motor_neurons

                                                                        Anton's syndrome

                                                                        Form of cortical blindness in which the patient is unaware of/denies the visual impairment; due to a lesion of the occipital lobe extending from primary visual cortex into visual association cortex

                                                                          Aphasia

                                                                          Inability to use language. It can either be a problem understanding language (receptive) or speaking it (expressive). People are often affected by both sorts. See: Dysphasia.

                                                                            Aphemia

                                                                            Inability to speak words despite being able to make other sounds

                                                                              Aphonia

                                                                              Complete loss of voice

                                                                                Aprasia

                                                                                An inability to perform purposeful movements

                                                                                  Apraxia

                                                                                  The inability to control and co-ordinate movements or carry out complex tasks when requested

                                                                                    Arachnoid

                                                                                    Middle layer of the meninges covering the brain and spinal cord

                                                                                      Arachnoid granulations (arachnoid villi)

                                                                                      Branched tufts of arachnoid that project through the dura mater into the venous sinuses and function to return CSF to the systemic circulation

                                                                                        Arachnoid villi

                                                                                        Diverticula of the arachnoid mater in the subarachnoid space that extend into the veins and venous sinuses of the dura; a major pathway for the drainage of cerebrospinal fluid and transport across the endothelium into the blood.

                                                                                          AROM

                                                                                          Active Range of Movement.

                                                                                            Aromatherapy

                                                                                            A therapy which employs aromatic plant-derived essential oils

                                                                                              Arcuate fasciculus

                                                                                              Pathway connecting Wernicke's area in the posterior left superior temporal gyrus to Broca's area in the left inferior frontal lobe; lesion results in impaired repetition

                                                                                                Area postrema

                                                                                                Chemoreceptor trigger zone for vomiting that is located on the dorsal surface of the medulla

                                                                                                  Argyll-Robertson pupil

                                                                                                  Pupil exhibiting light-near dissociation due to a lesion in the midbrain periaqueductal gray matter caused by tertiary syphilis

                                                                                                    Arousal

                                                                                                    Abrupt change from sleep to wakefulness

                                                                                                      Arteriovenous malformation

                                                                                                      A tangled collection of abnormal arteries and veins Click here for more information from the National Institute for Neurological Disorders and Stroke

                                                                                                        Arteritis

                                                                                                        Inflammation of an artery

                                                                                                          Arthrokinetic nystagmus

                                                                                                          Nystagmus induced by passive rotation of the arm of a stationary subject seated in total darkness inside a rotating drum

                                                                                                            Ascending tract of Deiters

                                                                                                            Direct pathway (lying just lateral to the medial longitudinal fasciculus) from the vestibular nuclei to the ipsilateral medial rectus subnucleus; clinical significance of this pathway is unclear

                                                                                                              Aseptic meningitis

                                                                                                              Syndrome characterized by headache

                                                                                                                Associated reactions

                                                                                                                Movements of body parts other than the ones that are intended to move

                                                                                                                  Association cortex

                                                                                                                  Cortical areas involved in higher order processing of sensory information and integration of multiple sensory and sensorimotor modalities

                                                                                                                    Astasia

                                                                                                                    Inability to stand because of motor incoordination

                                                                                                                      Astasia-abasia

                                                                                                                      Functional stance and gait characterized by bizarre movements

                                                                                                                        Asteriognosis

                                                                                                                        Inability to recognise objects by touch.

                                                                                                                          Asterixis

                                                                                                                          Sudden palmar flapping movement of the hands at the wrists; indicative of metabolic encephalopathy

                                                                                                                            Astrocytes

                                                                                                                            CNS glia that function to orient neuroblast migration in the cerebral and cerebellar hemispheres

                                                                                                                              Astrocytoma

                                                                                                                              Most common central nervous system tumor derived from astrocytes

                                                                                                                                Astrocytosis

                                                                                                                                Reaction of astrocytes to neuronal injury characterized by an increase in the number and size of astrocytes (primary reaction) and cytoplasmic changes including increased glial filaments and glassy eosinophilic cytoplasm followed by formation of a dense gliotic scar (secondary reaction)

                                                                                                                                  Asymmetrical

                                                                                                                                  Difference between two similar parts.

                                                                                                                                    Ataxia

                                                                                                                                    Lack of balance and uncoordinated movement.

                                                                                                                                      Athetosis

                                                                                                                                      Involuntary

                                                                                                                                        Atonia

                                                                                                                                        Loss of muscle tone

                                                                                                                                          Atonic seizure (drop attack)

                                                                                                                                          Generalized seizure characterized by sudden loss of muscle tone and strength; may cause the head to drop suddenly

                                                                                                                                            Attention span

                                                                                                                                            The length of time a person is able to concentrate on a given task.

                                                                                                                                              Attention problems

                                                                                                                                              Inability to sustain concentration because of competing stimuli or thoughts.

                                                                                                                                                Athetosis

                                                                                                                                                The term used to indicate a particular sort of uncontrollable movement and result from a particular brain lesion. It is present in the 'athetoid' type of cerebral palsy.

                                                                                                                                                  ATNR

                                                                                                                                                  Asymmetrical tonic neck reaction. When the face is turned to one side

                                                                                                                                                    Auditory agnosia

                                                                                                                                                    Failure to recognise specific sounds

                                                                                                                                                      Aura

                                                                                                                                                      Warning symptom

                                                                                                                                                        Automatism

                                                                                                                                                        Mechanical

                                                                                                                                                          Autonomic

                                                                                                                                                          Pertaining to the autonomic nervous system

                                                                                                                                                            Autonomic nervous system

                                                                                                                                                            Part of the peripheral nervous system that regulates visceral function and homeostasis independent of voluntary control.

                                                                                                                                                              Autoregulation

                                                                                                                                                              Physiological process by which blood vessels change caliber to maintain constant cerebral blood flow over a wide range of cerebral perfusion pressures.

                                                                                                                                                                Ax

                                                                                                                                                                Assessment.

                                                                                                                                                                  Axial

                                                                                                                                                                  Transverse plane producing a cross-section of the body or head.

                                                                                                                                                                    Axial Skeleton

                                                                                                                                                                    The bones of the skull

                                                                                                                                                                      Axon

                                                                                                                                                                      Long

                                                                                                                                                                        Axonal degeneration

                                                                                                                                                                        Neuropathic process resulting in degeneration of the axon and its myelin sheath; preferentially involves the distal portion of the axon.

                                                                                                                                                                          Axonal spheroid

                                                                                                                                                                          Stereotypic axonal response to injury consisting of marked swelling due to accumulation of materials undergoing axonal transport.